A hierarchical, stretchable poly(3-caprolactone)/ chitosan fibrous scaffold for rotator cuff tendon-bone healing

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Indomethacin and celecoxib impair rotator cuff tendon-to-bone healing.

BACKGROUND Nonsteroidal anti-inflammatory drugs are commonly prescribed after rotator cuff repair. These agents can impair bone formation, but no studies have evaluated their impact on tendon-to-bone healing. HYPOTHESIS Traditional nonselective nonsteroidal anti-inflammatory drugs and cyclooxygenase-2-specific nonsteroidal anti-inflammatory drugs interfere with tendon-to-bone healing. STUDY...

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Icariin Promotes Tendon-Bone Healing during Repair of Rotator Cuff Tears: A Biomechanical and Histological Study

To investigate whether the systematic administration of icariin (ICA) promotes tendon-bone healing after rotator cuff reconstruction in vivo, a total of 64 male Sprague Dawley rats were used in a rotator cuff injury model and underwent rotator cuff reconstruction (bone tunnel suture fixation). Rats from the ICA group (n = 32) were gavage-fed daily with ICA at 0.125 mg/g, while rats in the contr...

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Sclerostin Antibody Treatment Enhances Rotator Cuff Tendon-to-Bone Healing in an Animal Model.

BACKGROUND Rotator cuff tears are a common source of pain and disability, and poor healing after repair leads to high retear rates. Bone loss in the humeral head before and after repair has been associated with poor healing. The purpose of the current study was to mitigate bone loss near the repaired cuff and improve healing outcomes. METHODS Sclerostin antibody (Scl-Ab) treatment, previously...

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Enhancement of tendon-bone healing following rotator cuff repair using hydroxyapatite with TGFβ1

The formation of fibrocartilage at the healing site following a rotator cuff tear repair is a major problem in the field of tendon‑bone healing. The present study aimed to enhance the healing of the tendon‑bone interface following rotator‑cuff tear repair by the interposition of hydroxyapatite (HA) encapsulated with transforming growth factor β1 (TGFβ1). Using an acute rotator cuff repair model...

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Tendon trap technique for rotator cuff repair.

Strangulation around cuff tissue is a possible cause of retear after rotator cuff repair. Therefore, tendon healing ideally requires changes in suture tension over the cuff tissue in accord with rotator cuff muscle activity. The authors present a type of fixation that mimics the mechanism of the Chinese finger trap. The devised knot-free tendon trap technique resembles the double-pulley-suture ...

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ژورنال

عنوان ژورنال: Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology

سال: 2017

ISSN: 2214-6873

DOI: 10.1016/j.asmart.2017.05.292